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Author15 Posts
  #1

Pt w/ long hx of alcohol abuse has painless vomiting of bright red blood. H.R= 110/min and BP=80/0. Source of hemorrhage is found in the lower esophagus. Cause of hemorrhage?
a) Alcohol induced esophagitis
b) Deficiency in hepatic synthesis of Vit K dependent coagulation proteins
c) Mechanical tearing of the exophageal mucosa during vomiting
d) peptic ulceration of esophageal mucosa due to reflux of gastric acid
e) Transmission of portal HTN to exophageal veins.

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  #2

C (mallory weiss tears)

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  #3

answer-c-Im thinking (Mallory Weiss) thought more than just the mucosa
was involved.

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  #4

Yes agree with C

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  #5

why not E?? cirrhosis?
is mallory wies painless? i m unsure about it

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  #6

I agree with Mani. Painless vomiting does not suggest Mallory Weiss, quite on the contrary, since they think the tearing is caused by the effort when u vomit (there's a proper name for this... which I can't remember at the moment :-k ). Now, since the pt had a long history of alcohol abuse, it's very likely that esophagic vein ruptured as a consequence of portal HTN... caused by cirrhosis. E it is! <:flag:>

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  #7

Retching they call it ... that effort :-)
I d go for E.. painless is the key i think. Portal HTN due to Cirhosis, Esoph varicies, bleeding to stomach, then vomiting. The only thing is that blood may not be all that bright red.

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  #8

I agree "painless is the clue"..E seems the best choice

  #9

I cant see the words heartburn, esophagitis, odynophagia, dysphagia, the pain of esophageal ulcers (a complication of GERD) causing the same pain as gastric and duodenal ulcers :arrow: all referring to GERD being described as "painless vomiting."

M.W. can be with or without pain.
Boerhaaves syndrome is a severe esophageal rupture.
Esophageal varices involves a rupture of the l. gastric and azygous vein. I stand corrected because looking at the B.P. this kind of rupture would cause such a low B.P.

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  #10

Key words are long hx alcohol abuse, v. low bp indicating severe bleeding, painless vomiting of bright red blood and the source of the rupture is in the lower esophagus.

Leads me to say the answer is E.

I rule out a mallory weis tear based on the painless vomiting and the lack of a history of preceding retching/vomiting that did not contain blood.
Also correct me if I am wrong but are not mallory weis tears found in the anterior part of the gastro-oesophageal junction?

  #11

Yes the answer is E - this is an NBME question :-) :P

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  #12

My answer: E. Most likely cause of UGI bleeding:

1. PUD - 55%
2. Esophegeal varies - 14%
3. AVM - 6%
4. Mallory-Weiss Tear - 5%

The mortality rate for variceal bleeding from portal htn is 70-80% when left untreated. In contrast, a simple mallory-weiss tear (no portal htn) usually heal within 24-48 hours. (The patient died in my practice test-booklet que).

Why not mallory-weiss?
1. Is usually accompanied by preciptating factors causing intrabdominal pressure - retching, lifting, coughing
2. may accompany by epigastric or back pain
3. Is commonly accompanied by hx of vomiting or retching

Source:UTD

  #13

huMm It has to be .. (E) ... Esophageal Varix ..

But can some one tell me the relation of PAIN to Mally Wiess and Esop varices ? ! ...

And in this question is PAINLESS a clue .. I think .. the clue to the answer is Chronic Alchol intake ... and also that .. as others said Retching is NOT mentioned !

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  #14

"Addicudo" wrote:
huMm It has to be .. (E) ... Esophageal Varix ..

But can some one tell me the relation of PAIN to Mally Wiess and Esop varices ? ! ...

And in this question is PAINLESS a clue .. I think .. the clue to the answer is Chronic Alchol intake ... and also that .. as others said Retching is NOT mentioned !


M.W. may or may not present with pain, but varices bleeding is painless. My take is that this is evidence in favor of varices.

My take on the key to this Q is ETOH abuse in combination with the significant bleeding (BP 80/0) presentation. For M.W., pt may have ETOH abuse, but the bleeding presentation is usually non-lethal and self-healing in 24-48h. Other clues that are not in this case (no-pain, no retching episodes) make MW less likely.

  #15

very guud explanation grin

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