howto
Forum Senior
Topics: 30
Posts: 46
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Hi,
can anyone please explain about different types of blood a, b, o, ab and how one can have a reaction if transfused w/the wrong blood group. i mean, where are the antibodies, is it in the host's serum or rbc or the donor's. thanks for all your help
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| Idiopathic
Forum Guru
Topics: 19
Posts: 641
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The blood group antigens are located on the RBC's, while the antibodies are circulating in the plasma, as would be expected.
AB blood contains both A and B antigens, and therefore, no antibodies against either.
O blood contains neither A nor B antigen, and therefore, antibodies against both.
A blood has A antigen and B antibody; B blood has B antigen and A antibody.
SO, if someone with A blood is transfused with B blood, the Anti-B IgG that they have in their serum will hemolyze the donor RBC's.
AB is the universal acceptor (no antibodies)
O is the universal donor (no antigens)
An AB parent can never have an O child.
An O parent can never have an AB child.
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| howto
Forum Senior
Topics: 30
Posts: 46
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for your insights
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| Sakaki-
Forum Senior
Topics: 1
Posts: 238
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If the O parent has a Bombay phenotype, it is possible to have an AB child (rarely encountered in practice, however).
It is also important to keep in guide that transfusions can be of RBCs, plasma or platelets.
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