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Author4 Posts
  #1

what is it?

___________________
I leave no trace of wings in the air, but I am glad I have had my flight

  #2

This is a lesion to upper motor neurons that innervate cranial nerves. It is supranuclear because the lesion site is usually above the nuclei of the brain stem. Since most cranial nerve motor nuclei are bilaterally innervated by corticobulbar fibers, the most common sign is contralateral lower face weakness because the motor neurons of the facial nerve to the lower face are innervated only by the contralateral corticobulbar fibers.

  #3

neuroguy, may I know your resource of posting? From what I've read, supranuclear palsy is far more complicated than just CN VII palsy. It involves CN III, basal ganglia and substantia nigra. but I have a hard time organizing my thoughts and fill them all into one disease. Again, what does supranuclear/subcortical site mean specifically?

___________________
I leave no trace of wings in the air, but I am glad I have had my flight

  #4

Supranuclear palsy is more often used in relation to parkinsonian+dementia syndromes where there is loss of vertical conjugate gaze movements which are controlled at a cortical level with different areas contributing for different aspects like

frontal eye filed for voluntary fixation
parietal for pursuit

supranuclear palsy is a degeneration of these areas/pathways which lead to loss of vertical conjugate gaze movements.

thank you







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