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Kaplan Qbank USMLE



Author19 Posts
  #1

Whats the most ccommon cause of primary amenorrhea?

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  #2

The main cause of primary amenorrhea is late puberty.

  #3

Answer- Pregnancy

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  #4

ans; pregnancy

  #5

how would u distinguish 1 and 2 AMA by labs ?

  #6

how can a patient with primary amen be pregnant???????? :roll:
pregnancy is the commonest cause of secondary amen :!: :!:

  #7

I agree too cant be pregnancy

  #8

Hi,
The most common reason of primary amenorrhea is delayed puberty.
The most common reason for secondary amenorrhea - pregnancy.
You don't need labs to differentiate between primary and secondary, it's the definition. Primary - is not having menstrual periods by the age of 16, secondary - absence of three or more periods in a woman who has had regular menstrual periods.

  #9

1 AMA...increased lsh and fsh ..decresed estrogen ... turners syndrome

2 AMA ... decresed lsh , fsh and estrogen .....in anorexia nervosa

  #10

I stand corrected, the q was suppose to be the most common cause of amenorrhea not primary amenorrhea. Gonadal agenesis accounts for one third of all cases of all patients with amenorrhea eg Turners Syndrome.

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  #11

I stand corrected, the q was suppose to be the most common cause of amenorrhea not primary amenorrhea. Gonadal agenesis accounts for one third of all cases of all patients with primary amenorrhea eg Turners Syndrome.

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  #12

45xo

  #13

what is lsh?? sad

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Emily

  #14

Primary amenorrhea is not considered to have occurred until a girl is beyond age 16 without the onset of menses, if she has undergone other normal changes that occur during puberty. Primary amenorrhea may occur with or without other signs of puberty.

There are multiple causes for primary amenorrhea:

Normal delay of onset (up to age 14 or 15)
Drastic weight reduction (resulting from poverty, fad dieting, anorexia nervosa, bulimia, very strenuous exercise, or other cause)
Congenital abnormalities of the genital system (absence of the uterus or vagina, vaginal septum, cervical stenosis, imperforate hymen)
Hypoglycemia
Extreme obesity
Gonadal dysgenesis
Chromosomal abnormalities such as Turner's syndrome (XO), or Swyer's syndrome (XY)
Hypogonadotropic hypogonadism
Testicular feminization syndrome
True hermaphroditism
Chronic illness
Malnutrition
Cushing's disease
Cystic fibrosis
Congenital heart disease (cyanotic)
Craniopharyngioma, ovarian tumors, adrenal tumors
Hypothyroidism
Galactorrhea
Adrenogenital syndrome
Prader-Willi syndrome
Polycystic ovarian disease
Congenital adrenal hyperplasia
Pregnancy (also!)

  #15

where can i read more about Swyer's syndrome(XY)?
thanx in advance

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  #16

Swyer’s SyndromeWhat is it?Swyer’s syndrome belongs to a group of conditions known as gonadal dysgenesis. This iswhere the gonads (testes or ovaries) do not form in the usual way, and this occurs to ababy during to first few weeks of pregnancy. Girls with Swyer’s syndrome have XY (usualmale) genes.This condition was first described by Dr G Swyer in the 1950’s. Swyer’s syndrome is achance occurrence and does not run in families.What causes it?Normally, a Y chromosome encourages male development, and prevents a wombdeveloping. The gonads usually help with this. In Swyer’s syndrome the Y chromosomeand the gonads do not function in the usual way, so a womb (uterus), vagina, clitoris, andlabia (vaginal lips) develop. The gonads are present as small “streaks” near the womb.30% of the time, this is due to a specific change in part of the Y chromosome, which ispresent from when a baby is conceived. The rest of the time, reasons are unclear.How is it diagnosed?Not all of the usual puberty changes happen when they should. Usually it is diagnosedwhen the periods have not started, and there is also little or no breast development. This isbecause the gonads are not able to release hormones which would normally control this, soalthough there is a womb present, there are no hormones to make periods. These samehormones would have been responsible for breast development.How is it managed?The gonads are not functioning in the usual way, and are not giving any hormones fordevelopment. Hormone replacement therapy (HRT) is given to allow breasts to grow, andto develop the normal female body shape. HRT also keeps the bones strong and helpsprevent thinning of the bones (osteoporosis) from occurring in later life.In addition, there is a 30% chance of some cancer cells developing in the gonads. For thisreason it is important that they are removed, and this is normally done before puberty.Nowadays this can be done with “keyhole surgery”.What about Fertility?Women with Swyer’s syndrome cannot have their own genetic baby as the original gonadsdid not contain any eggs. However, it is possible for women to carry a pregnancy withdonated eggs. These could be fertilised with her partner’s sperm, and the pregnancy couldbe implanted back in the womb. She would then need to have hormones to help nourishthe pregnancy.SUMMARY• XY genes• Normal female genital area• Womb and vagina present• “Streak” gonads which have a 30% risk of becoming cancerous• Gonads removed and HRT given• Carrying a pregnancy possible, using donated eggsMore InformationYou may find the following links useful.www.medhelp.org/ais

  #17

smiling face Thank you for the detailed reply! smiling face

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  #18

Turner syndrome 45 XO

  #19

"EMI777LY" wrote:
what is lsh?? sad

LH ,FSH

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