Idiopathic Forum Guru
Topics: 19 Posts: 641
| | 06/03/04 - 09:17 AM  
 
   
 
|   #2 |
Wegeners...affects nose, lung and kidneys. Vasculitis that is c-ANCA positive and that is treated with cyclophosphamide in some cases, which is known for cauing hemorrhagic cystitis and transitial cell CA of the bladder.
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| mjl1717 Forum Hero

Topics: 958 Posts: 5,463
| | 06/03/04 - 01:25 PM  
 
   
 
|   #3 |
The first thing I think of is focal necrotizing vasculitis and necrotizing granulomas in the lung. In addition to what Idiopathic says. I think the boards would give a little more history.
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| mingle Forum Senior
Topics: 27 Posts: 109
| | 06/03/04 - 06:33 PM  
 
   
 
|   #4 |
well the key thing is ashma which points to only one condition on the list---churg strauss... churg strass could be c-anca positive(70%) or negative & it usu presents with asthmatic symptoms in the middle aged with haematuria haematochezia & haemoptysis. microscopic polyangitis has the same latter 3 signs but without the asthmatic symptoms. wegners does cause the symptoms but there is no association of it with asthma
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| Idiopathic Forum Guru
Topics: 19 Posts: 641
| | 06/03/04 - 07:40 PM  
 
   
 
|   #5 |
You got me on that...I read right over it. Churg-Strauss is a vasculitis with asthma/eosinophilia. I did not know about the renal involvement though. VERY good question.
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| mingle Forum Senior
Topics: 27 Posts: 109
| | 06/04/04 - 05:04 AM  
 
   
 
|   #6 |
thanks i thought that might stump a few while reading
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| mani Forum Guru

Topics: 104 Posts: 1,403
| | 06/04/04 - 04:23 PM  
 
   
 
|   #7 |
churg straus is thought to be a variant of PAN with pulm involvemnt and eiosinophilia. As renal involvment occurs in PAN so i guess renal involvement would be there in churg straus
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