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 quest 2 !!take a look  




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Author8 Posts
  #1

MAVLELHSIKKLSTI (wildtype)
MAVLECTALKN (mutant)

Two genes are expressed, one wildtype and one mutant. The sequences of the gene products are provided above. What is the likely mutation?

A. Deletion of 6th codon
B. Deletion of nucleotide in 6th codon
C. Insertion of stop codon
D. Substitution of 13th codon
E. Substitution of 6th codon




  #2

its B.. a frameshift mutation..


  #3

right..nod


  #4

rightnodnod


  #5

can anyine explain me this?


  #6

the mutant one is shorter and the whole AA sequence after the 5th AA has been changed..


  #7

thanx! a3112nod


  #8

EACH LETTER REPRESENT SINGLE AA=SINGLE CODON LIKE V=VALINE ,
WHEN HE SAID DELETION OF 6TH CODON=(L)AA
SO IN MUTANT GENE ALL AA DISTAL TO(E) HAS BEEN CHANGED=FRAME SHIFT





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