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dr_elreifai85 Forum Junior Topics: 24 Posts: 225	Apr 07, 2009 - 1:53 AM       #1 can any one explain wh happen 2 k plasma concentration k intracellular conc renal k excretion k balance in the following cases acute and chronic alkalosis acute and chronic acidosis it was achart in kaplan renal video so any one ???
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dr_elreifai85 Forum Junior Topics: 24 Posts: 225	Apr 08, 2009 - 3:58 AM       #2 any one ?????????????
wishikhan Forum Newbie Topics: 93 Posts: 278	Apr 11, 2009 - 1:22 PM       #3 IN ACIDOSIS hydrogen ions enter from ECF into the cell and potassium leaves the cell so there is Hyperkalemia IN ALKALOSIS reserve will occure ie hydrogen enter the ECF and potassium enters the cell so HYPOKALEMIA occurs . positive potassium balance occurs when excretion is less than intake negative when excretion is more than intake . in acute alkalosis the plasma potassium will decrease ,intracellular will increase ,renal excretion will increase and the k balance will be negative as excretion will be more than intake in chronic alkalosis plasma potassium will decrease ,intracellular will decrease and renal excretion will increase and there will be negative potassium balance . in acute acidosis plasma potassium will increase intracellular will decrease renal excretion decreases and there will be positive potassium balance. in chronice acidosis plasma potassium is increase intracellular decreases because the major cellular mass loss potassium ie increased excretion of potassium distal tubular cells have increase potassium concentration because of K+-H+ SHIFT THUS POTASSIUM EXCRETION DEPLETS THE BOY . the major difference between acute and chronic acidosis is that in chronic there is a negative potassium balance
dr_elreifai85 Forum Junior Topics: 24 Posts: 225	Apr 13, 2009 - 6:39 AM       #4 thanx 4 reply but how in acute - chronic alkalosis the plasma potassium will decrease and ,renal excretion will increase ? and how in acute acidosis plasma potassium will increase and renal excretion decreases ?
wishikhan Forum Newbie Topics: 93 Posts: 278	Apr 13, 2009 - 9:46 AM       #5 in acidosis H ions enter the cells to be buffered in large part by protein and in order to maintain electrical neutrality potassium comes out . hydrogen and potassium ions both have positive charge . as potassium comes out it causes increase in potassium concentrration in ECF .increase in potassium concentration is HYPERKALEMIA ... if potassium concentration is increased in ECF so this means decreased excretion of potassium . in acute and chronice alkalosis reverse will occur i hope it makes sense this time
dr_elreifai85 Forum Junior Topics: 24 Posts: 225	Apr 14, 2009 - 11:10 AM       #6 yes now its clear i was thinking in acidosis >> increase k plasma concentration so eventually it ll lead 2 increase it renal excretion

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