mash
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Which of the following types of inhibition have been identified within the dorsal column nuclei?
A. Feed-forward inhibition utilizing local interneurons only
B. Feedback inhibition utilizing local interneurons only
C. Distal inhibition from fibers arising in the cerebral cortex only
D. Feed-forward, feedback, and distal inhibition
E. Feed-forward and distal inhibition only
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| rida
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Just a guess E??
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| mani
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i m sure about feed back as well. rida, the effect of golgi tendon organ is a clear example of feedback inhibition. so my guess is D
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| mash
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it is D
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| mash
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it is D
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| rubensssss
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If we are talking about dorsal colum nuclei, is only second order neuron, how it could be distal inhibition.Is there and explanation?
Sorry probable I misunderstood the question.
First order neuton----Dorsal root and spinal cord ganglion
Second order neuron--- Spinal cord
Third order neuron-----Thalamus
Fourth order neuron--- Sensory area cerebral cortex.
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| mash
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To generate an excitatory focus with an inhibitory surround, three types of inhibition are present in the dorsal column nuclei. First-order neurons ascending in the dorsal columns make synaptic contact with different cells in the dorsal column nuclei and excite those cells. One such cell may be an inhibitory interneuron that makes synaptic contact with a neighboring dorsal column nuclear cell, thus inhibiting that cell (i.e., feed-forward inhibition). In addition, the dorsal column cell that is excited by the first-order neuron may make synaptic contact with another inhibitory interneuron (in addition to its classical ascending projection to the ventral posterolateral nucleus of the thalamus). This inhibitory interneuron makes synaptic contact with an adjacent dorsal column cell and inhibits that cell (i.e., feedback inhibition). Finally, a descending fiber from the postcentral gyrus can make synaptic contact with inhibitory interneurons that inhibit dorsal column cells.
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| rubensssss
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thanks mash, I am still thinking it shoul be CNS instead of dorsal colum nuclei; What do you think?
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| rubyduby
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can any one expalin it a little more easier way , i will go back to kaplan nuroantamoy corticospnal trct, i think they expalined there,but i dint understand dat golgi tendon concpt there. as far as i know dorsal colum medial lemniscus is sensory tract and it goes to forward direction means to thalamus..but anyways pls eany one xpalin me wat these interneurons are doing here?
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Hi,
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| mani
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gosi tendon organ is given in BRS neurophysiology
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