suvi21
Forum Junior
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Here's a Q by Dr. Costanzo; I think this is a very good integrative Q. If you can do it with explanations, it summarizes all of ECF/ICF homeostasis.
A woman runs the New York City Marathon on a 90°
day. It is determined that she loses 3 liters of sweat,
which is hypotonic. During the marathon, she drinks
3 liters of H2O. For each parameter listed below,
indicate whether it is increased, decreased, or unchanged
in the new steady state,( explain your ans pls)
Plasma osmolarity
ECF volume
Hematocrit
Total body water
ICF volume
ICF osmolarity
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| dranuragagrawal
Forum Newbie
Topics: 2
Posts: 21
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only answers...
i think due to loss of salt just consider that
plasma osmolal decreased
ecf volume decreased
hct increased??
total body same
icf vol increased
icf osm. decreased
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| mani
Forum Guru
Topics: 104
Posts: 1,403
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1.decreased
2.decreased
3.increased
4.unchanged
5.increased
6.decreased
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| suvi21
Forum Junior
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 . Good job
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| mani
Forum Guru
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its good to keep D Y diagrams for such questions
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| marble
Forum Newbie
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How is total body water the same if she lost 3 L's?
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| Sakaki-
Forum Senior
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Because she drank 3 L of water.
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| marble
Forum Newbie
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I see said the blind man. I was tired when I read it, that's my excuse... lol
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| Sakaki-
Forum Senior
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Haha--don't worry; we all do that. 
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| rubyduby
Forum Newbie
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she is sweatign as quesion said hypotonic loss. so u loose more water (ecf...decreases intially) than salt so osmolarity shud increase.. and as result of which icf will shrink(dec) and ecf will increase LATER not only becuz of volume shift from icf to ecf as well of 3liters water ingestion.. overall tbw remains same becuz she lost 3 liters while sweting so got back 3 litres by ingestion.
thus is question is but confuse can any one pls explain those changes before and after ingestion of fluids. i appreciate
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Hi,
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| mani
Forum Guru
Topics: 104
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the suestion also says that she made up the lost volume bt drinking water. so volume replaced with no electrtolyte replacement. now loss is hypotonic or hypertonic?
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| Sakaki-
Forum Senior
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All they meant was hypotonic to the plasma, which means that there was a net loss of water (relative to salt) (from the sweating alone), as you said, rubyduby. But as mani pointed out, we need to take the intake into consideration as well.
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