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Author5 Posts
  #1

5 yo girl with developing breasts. Has large hyperpigmented macules w/ irregular margins on one side of her back. Diagnosis?

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La vita e bella!

  #2

adrenogenetal syndrome, i think 17 alpha hydroxylase dedficiency

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  #3

albright syndrome?

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I hear and I forget. I see and I remember. I do and I understand.
--Confucius

  #4

Very good, mash! It is Albright's. Can u elaborate? Thnx!

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La vita e bella!

  #5

albrights is ch by precocious puberty(autonomous endocrine hyperfunction),
cafe-au-lait spots and polyostotic fibrous dysplasia.
females r affected more than males
changes in ovary, bone, and skin tissue are most common, other endocrine and nonendocrine tissues also may be affected, including the adrenal, thyroid, pituitary, liver, and heart.
The most common form of autonomous endocrine hyperfunction in this syndrome is gonadotropin independent precocious puberty, but affected individuals also may have hyperthyroidism, hypercortisolism, pituitary gigantism, or acromegaly. Nonendocrine abnormalities in this disorder include hypophosphatemia, chronic liver disease,

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I hear and I forget. I see and I remember. I do and I understand.
--Confucius







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