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given the following blood type of a couple planning to have children, which of the following must be an offspring of the couple?
Mother: AB, MN, Rh-
Father: 0, MN, Rh-
A) B, MN, Rh+
B) 0, MN, Rh-
C) B, MN, Rh-
D) O, M, Rh-
E) AB, MN, Rh-
The response to the question is what confused me, if anyone could explain this to me I'd appreciate it. Also maybe a little 101 on the whole MN, Rh thing and the antigen to offspring. The answer to the question is as follows:
Because the father has no blood type antigen, the offspring will inherit either an A or B antigen from the mother and never can be an O blood type. Similarly, because both parents have the M and N antigen, the offspring can inherit either antigen from either parent. Both parents are Rh-, so the offspring must inherit the Rh-. As a consequence, option A, B, C and E are all genetically impossible outcomes from the given parental genotype.
The answer should be C, since,
-the kid MUST be Rh- :rules out A
-the kid should be either AO or BO [can't be OO or AB] : rules out B,D,E..
so its C.
PS :Not sure how the MN groups work..
ya answer shld be C
i am asking a very easy question plz exp BLOOD TYPING . its a very easy concept but i am so confused in it . i have asked this question many times before but no body replied
Yes, its C
I would also say C
The parents are AB and 0 (00) => the kid should be A0 or B0.
If both parents have MN, the kid should also have MN.
In the Rh blood group system the most important antigen is D. If the parents both are Rh- I assume they both have dd (antigens), so the kid will also have dd => Rh-
C- CHILD HOMOZYG. TO N GIVE N BLOOD BROUP
CHILD HOMOZ.TO M GIVE BLOOD GROUP M
child heterozyg. to M and N GIVE MN BLOOD GROUP
NOTE;M ALLELE ENCODE SERINE AA IN RBC GLYCOPROTEIN
N ALLELE ENCODE FOR LEUSINE IN RBC
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