mash
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A
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| Idiopathic
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specificity based on heterophile antibodies, as many things cause atypical lymphocytosis.
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| mjl1717
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I agree with Idiopathic--Heterophile antibody is the gold standard/ sometimes the Monospot test. [I see that these test are normal in patients without disease]
The atypical lymphs or "Downey Cells" is only some guy trying to get his name in history.
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| Rachana
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The answer given was B. Which I think is totally wrong. I would go with C. Heterophile anitbodies.
Does anybody have any more information abt this?
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| Bela
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Yeah, initially I picked C because it specifically says MONO caused by EBV.
If they didn't specify that, then C could not be the right answer b/c if the patient has a +heterophile activity, the cause is EBV. If it's -, think about CMV, HIV, Toxo. So, heterophility just helps you determine the cause of Mono, not whether the pt has mono or not.
I remember the kaplan professor mentioned that dx of Mono is by detecting IgM :?
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| exeon
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C
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| docface
Forum Senior
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answer is a as the question refers for specificity of the test, not sensitivity.
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| bluestar
Forum Guru
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apart from the atypical lymphocyte, could EBV-specific IgM or IgG Ab be the answer?
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