Rachana
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A 28-year-old man undergoes induction chemotherapy for acute myelogenous leukemia. A week later he becomes severely pancytopenic, with a WBC count of 1320/microliter, Hgb 7.9 g/dL, and platelet count of 72,000/microliter. He becomes comatose a day later. A CT scan of the head reveals a right parietal hemorrhage. He dies a day later. At autopsy, he is found to have a right middle cerebral arterial thrombosis with right parietal hemorrhagic infarction. Which of the following infectious agents is most likely to cause these findings?
A Herpes simplex virus
B Toxoplasma gondii
C Human immunodeficiency virus
D Cytomegalovirus
E Aspergillus niger
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| intern_doc
Forum Guru
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I think it's A
HSV produced hemorrhagic necrosis
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| Rachana
Forum Junior
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(E) Aspergillus loves to invade blood vessels and produce thrombosis. Neutropenia is a risk for aspergillosis. Also Mucor has predilection for blood vessels.
Source: Kaplan lecture notes.
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| intern_doc
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oK...THANX
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