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Kaplan Qbank USMLE



Author7 Posts
  #1

what are different basic types of necrosis??

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  #2

basic r
coagulative
liquefactive
fibrinoid
fat
caseous is combi of coagulative & liquefactive
gangrenous--- wet is liquefactive
dry is coagulative

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  #3

Thee most common is coagulative (denature proteins),canbe due to ischemia,heavy metal and radiation.
Pale infarcts in solid organs heart ,kidney spleen
Hemmorhagic(red) infarcts in loose textured organs , bowel lung ovary

Liquefactive can be due to enzymes from neutrophils (lung abscess) brain
Fibrinoid think immunologic
Fat-pancreatic enzymes

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  #4

Fat necrosis also occurs in trauma of breast...but I don't think it is due to pancreatic enzymes.

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  #5

fat necrosis can be traumatic or enzymatic
traumatic is non enzymatic
enzymatic in pancreas

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I hear and I forget. I see and I remember. I do and I understand.
--Confucius

  #6

the point i wanted to emphasize is "basic". i think fibrinoid necrosis doesnt fullfill the definition of "necrosis". its just a name for a physiacal change ie depositoin of fibrinoid material in the vessel wall. actual necrosis if present would be in the organ supplied and would be coagulative. moreover i think fat necrosis would be of liquifactice type both in enzymetic and traumatic types. so basically we have 2 types of necrosis, liquifactive and coagulative

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  #7

i think mani is right .







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