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Author4 Posts
  #1

can anybody explain the ecf vol, icf vol changes in pri.polydypsia and central neurogenic diabetes insipidus.

seems lil confusing......

  #2

I think there is increase concentration of ecf and diluted urine because there is no relese of ADH so there is increase urine which is diluted and leave concentrated plasma ecf behind

  #3

both pri polydipsia and neurogenic DI ve decreased ADH so, both r ch by large vol of dilute urine => urine vol is inc and osmolarity is decreased

diff. b/w the 2 is
pri polydipsia is hyposmolar i.e. ecf vol is inc and osmolarity is decreased
icf vol is inc and osm is dec ( bcoz of excess water intake => ecf inc and osm decreases => icf vol inc and osm decreases)

central DI is hyperosmolar i.e ecf vol is dec and osm is inc
icf vol is dec and osm is inc (dec ADH => inc dilute urine => dec ecf vol and inc ecf osm => dec icf vol and inc icf osm)

___________________
I hear and I forget. I see and I remember. I do and I understand.
--Confucius

  #4

Thanks mash !! smiling face







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