NNL
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A 35-year-old man who presents with a neck mass is found to have a serum calcium level of 11.8 mg/dL and periodic elevation of his blood pressure. Extensive workup reveals the presence of a medullary carcinoma of the thyroid, a pheochromocytoma, and hyperplasia of the parathyroid glands.
Which of the following is the most likely diagnosis?
a. Multiple endocrine neoplasia syndrome type 1
b. Multiple endocrine neoplasia syndrome type 2A
c. Multiple endocrine neoplasia syndrome type 2B
d. Polyglandular syndrome type I
e. Polyglandular syndrome type II
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Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck
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| loto
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B
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| SILVER
DoWhatYouGotToDo!
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B
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Stop telling God how big your storm is. Instead, tell your storm how big your God is. To succeed it is necessary to accept the world as it is and rise above it. Success is failure turned inside out, the silver tint on the clouds of doubt.
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| keepgoing
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b
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| brainstem
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B
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| NNL
Awaitin The Unexpected
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loto wrote:
B
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Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck
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| NNL
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The answer is b.
Combinations of neoplasms affecting different endocrine organs in the same patient are referred to as multiple endocrine neoplasia (MEN) syndromes.
There are several types of MEN syndromes. Patients with type 1 MEN syndrome (Wermer’s syndrome) have pituitary adenomas, parathyroid hyperplasia (or adenomas), and neoplasms of the pancreatic islets. The latter most commonly are gastrinomas, which secrete gastrin and produce Zollinger-Ellison syndrome. Type 2A MEN syndrome (Sipple’s syndrome) is characterized by the combination of medullary carcinoma of the thyroid, pheochromocytoma of the adrenal medulla, and hyperparathyroidism.
MEN type 2B syndrome (also known as type 3) is associated with medullary carcinoma of the thyroid, pheochromocytoma of the adrenal medulla, and multiple mucocutaneous neuromas.
In contrast to the MEN syndromes, combinations of autoimmune diseases affecting different endocrine organs are called polyglandular syndromes. There are several types of polyglandular syndromes. Patients with type I polyglandular autoimmune syndrome have at least two of the triad of Addison’s disease, hypoparathyroidism, and mucocutaneous candidiasis.
Type II polyglandular syndrome (Schmidt’s syndrome) is not associated with either hypoparathyroidism or mucocutaneous candidiasis, but instead is associated with autoimmune thyroid disease (Hashimoto’s thyroiditis) and insulin-dependent diabetes mellitus.
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Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck
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| maoudoody
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the first one of those questions i found easy!!!!!!
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