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Falcon USMLE
Did you find this easy
Yes 33%
new_n_lost
1 33%
NO 67%
brainstem, Ferritin
2 67%
3 votes


Author7 Posts
  #1

A 51-year-old woman presents with problems seeing and drooping eyelids. She had been diagnosed 5 years prior as having lupus. A chest x-ray reveals a mass in the anterior mediastinum, which is confirmed by a CT scan. Surgical exploration finds a well-encapsulated tumor. No evidence of invasion is seen. The mass is resected, and histologic sections reveal scattered lymphocytes within a diffuse proliferation of spindle-shaped cells.

Which of the following is the cell of origin of this tumor?

a. Epithelial cells of the thymus
b. Fibroblasts of the mediastinal mesenchyme
c. Follicular cells of ectopic thyroid tissue
d. Immature T lymphocytes of the thymus
e. Mesothelial cells of the mediastinal mesothelium



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Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck

  #2

A thymoma


  #3

A



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  #4

a



  #5

A


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  #6

loto wrote:
A thymoma


nodnod



___________________
Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck

  #7

The answer is a.

Thymomas are tumors arising from thymic epithelial cells and are among the most common mediastinal neoplasms, especially in the anterosuperior mediastinum. Histologic sections reveal a proliferation of spindle-shaped cells. There is a scanty or rich lymphocytic infiltrate of T cells, which are not neoplastic, although their size and prominent nucleoli may cause histologic confusion with lymphoma. About 90% of thymomas are benign and occur at a mean age of 50 years. They are very rare in children. They may be asymptomatic or may cause pressure effects of dysphagia, dyspnea, or vena cava compression. Associated systemic disorders include myasthenia gravis, hematologic cytopenias, collagen vascular disease (lupus), and hypogammaglobulinemia. Malignant thymomas show infiltration and capsular invasion plus pleural implants or distant metastasis.


In contrast, the other type of cell found in the thymus, T lymphocytes; give rise to T-cell lymphoblastic lymphomas. Finally, recall that fibroblasts give rise to fibromas or fibrosarcomas, and mesothelial cells give rise to benign or malignant mesotheliomas.



___________________
Tyrants and Occupiers of territories tend to think, act and feel alike "Never argue with fools, they'll bring you down to their level & beat you with experience" “The Pure and Simple Truth is RARELY Pure and Never Simple" It is with words as with sunbeams, the more they are condensed, the deeper they burn Would You Dare to Think Different PS I get enough exercise just by pushing my luck









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