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Kaplan Qbank USMLE



Author11 Posts
  #1

Could some one explain me in detail that how "INSERTION SEQUENCE SHOWING TERMINAL INDIRECT REPEATS+ GENES FOR TRANSPOSITION" work? This is shown on page 210 of kaplan notes of microbiology/Immunology
IS THIS NOT IMPORTANT?

  #2

yep its imp topic..

Read it once again ,If you don't understand i' will explain you.

  #3

THANX ASMI.I UNDERSTAND WHAT R TRANSPOSONS.PLS EXPLAIN ME THIS TOPIC.
THANX ASMI ONCE AGAIN.

AND ONE MORE Q.

pls explain me what is lysogency?
i know if repressor damage it goes in lytic cycle,but i don't understand regarding the lysogency of OBED
O= FOR SOLMONELLA
B=BOTULINIUM
EXOTOXINS A-C OF STRP PYOGENES,
D=DIPHTHERIA.
PLS EXPLAIN ME WITH EXPLANATION.
THIS WHOLE STORY IS ONPAGE 223 OF KAPALAN MICRO.
THANX IN ADVANCE

  #4

THANX ASMI.I UNDERSTAND WHAT R TRANSPOSONS.PLS EXPLAIN ME THIS TOPIC.
THANX ASMI ONCE AGAIN.

AND ONE MORE Q.

pls explain me what is lysogency?
i know if repressor damage it goes in lytic cycle,but i don't understand regarding the lysogency of OBED
O= FOR SOLMONELLA
B=BOTULINIUM
EXOTOXINS A-C OF STRP PYOGENES,
D=DIPHTHERIA.
PLS EXPLAIN ME WITH EXPLANATION.
THIS WHOLE STORY IS ONPAGE 223 OF KAPALAN MICRO.
THANX IN ADVANCE

  #5

HEY ASMI WHERE R U?
U DIDN'T EXPLAIN ME?

  #6

hi santaclara,

Iam extremely busy..since iam not in town .will definately reply u after 3 or 4 days.

Sorry for the delay :oops:

  #7

ok well i will wait for u.
pls reply me.and explain me.
thanx. smiling face

  #8

Lysogeny :arrow: incorporation of prophage into chromosome.

lysogenic conversion :arrow: change in pathogenicity due to prophage.

About OBED ...can u repeat ur Q..?

  #9

hello asmi
Could some one explain me in detail that how "INSERTION SEQUENCE SHOWING TERMINAL INDIRECT REPEATS+ GENES FOR TRANSPOSITION" work? This is shown on page 210 of kaplan notes of microbiology/Immunology
IS THIS NOT IMPORTANT?
(this is first Q which i asked u?)
and another Qwhich i asked is that i understand now LYSOGENY and LYSOGENIC CONVERSION.
but what is that phage-coded pathogenic factors or lysogenic conversion?will they more pathogenic after phage or some thing else and these r four organisms(OBED).u can see this on page 209. of kaplan micro and immuno.
pls explain me both.
thanx asmi for reply.

  #10

Hi ,

Transposons/jumping genes have sequence of indirect repeats of bases on each ends(they read identically from each opp. ends) and in middle is the transposase gene (examle:drug resistance genes).

Transposase enzymes are responsible for cleavage of dsDNA.Transposase recongnise specific sequence of nucleotides and these transposons/jumping genes inserts into DNA molecule.This insertion creates direct repeats on each side of transposons,known as insertion sequences.

:idea: just remember the defination of transposons and its use for exam.

OBED :arrow: yes , they r example for lysogeny and the given organisms become more pathogenic,since phage mediated mechanism of toxin production or antigen production.

Hope this helps.

  #11

thanx asmi for reply.
i think u r right b/c as i listened the kaplan video also the teacher also said same thing just to remember def of transposons.
but asmi as i told u that i m not understanding the direct and indirect repeats ("INSERTION SEQUENCE SHOWING TERMINAL INDIRECT REPEATS+ GENES FOR TRANSPOSITION" work? which is shown on page 210 of kaplan,is that imp or not?
pls tell me this.
i understand your reply
thanx.
good luck.







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