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Kaplan Qbank USMLE



Author4 Posts
  #1

The action of angiotensin 2 on kidney is:
A. increases Na reabsorbtion in principal cells of distal tubule
B. increases H2O permeability in distal tubule
C. increases Na-H exchange and HCO3 reabsorbtion in proximal tubule
D. increases GFR

Match the hormone with their mechanism of action in the kidney:
A. ADH
B. PTH
C. aldosterone
D. ANF

1. Adenylate cyclase-cAMP
2. Protein synthesis
3. Guanylate cyclase
4. Ca-IP3[/list]

  #2

First Q) C

Second Q)
a 1 and 4 i believe depending on V1 or V2 receptor
b 1
c 2
d 3

___________________
"If He takes you to it, He'll take you through it."

  #3

AT-II actually increases GFR in the kidney (directly) and activates aldosterone (indirectly). The efferent arteriolar pressure is dependent on AT-II, and this is why you cannot give someone with bilateral renal artery stenosis an ACE-inhibitor, because the only thing they have regulating their GFR is the outflow (or the efferent arteriole)

If asked, PGE2 regulates afferent arteriolar pressure and AT-II regulates efferent arteriolar pressure (it also constricts the mesangium at high concentrations).

  #4

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