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Rachana
Forum Junior

Topics: 23
Posts: 52
05/13/04 - 02:00 PM       #1

I am a new user...

Anyways, Are competitive inhibitors similar to comp antagonists? Do they increase or decrease Km...what abt non comp?
Thanks in advance...

Rachana

whereami
Forum Newbie

Topics: 0
Posts: 20
05/13/04 - 03:39 PM       #2

They sound synonymous to me, but I'm not sure.

Competitive inhibitors will increase Km, as they compete with the normal substrate for enzyme's active site.

Non-competitive ones do not affect the Km, but they reduce the enzyme's Vmax.

samsung
Forum Newbie

Topics: 5
Posts: 17
05/18/04 - 08:32 AM       #3

"Rachana" wrote:
I am a new user...

Anyways, Are competitive inhibitors similar to comp antagonists? Do they increase or decrease Km...what abt non comp?
Thanks in advance...

Rachana


Yes, they are synonym

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