mash
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i think vitamin B12 def
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| mash
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wats d ans?
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| piter
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thiamine???
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| Idiopathic
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peripheral neuropathy due to pyridoxine deficiency? (B6)
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| santaclara
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peripheral neuropathy ALSO OCCUR B/C OF VITB12.
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| Idiopathic
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vitamin B12 causes combined subacute degeneration. Loss of fine touch and proprioception, but I dont think paraesthesia is part of B12 deficiency.
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| santaclara
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HEY IDIOPATHIC I SAID peripheral neuropathy ITHINK WHICH OCCURE B/C OF VIT B6 AND VITB12 BOTH.
PLS CORRECT ME IF WRONG.
I READ THIS FROM BIO KAPALAN.
GOOD LUCK. 
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| mash
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Neurologic sequelae from vitamin B12 deficiency include paresthesias, peripheral neuropathy, and demyelination of the corticospinal tract and dorsal columns (subacute combined systems disease).
http://www.aafp.org/afp/20030301/979.html
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I hear and I forget. I see and I remember. I do and I understand.
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| santaclara
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AM I WRONG MASH? :roll:
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| mash
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no santaclara u r right ,peripheral neuropathy can occur with def of both B12 n B6
pt is agitated n has paraesthesia too so i think ans is B12 def .
wat do u say?
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I hear and I forget. I see and I remember. I do and I understand.
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| santaclara
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i think so mash.
but again i will read that topic and u also pls.
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| mash
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Signs of vitamin B6 deficiency include dermatitis (skin inflammation), glossitis (a sore tongue), depression, confusion, and convulsions
Vitamin B6 is needed for the synthesis of neurotransmitters such as serotonin and dopamine . These neurotransmitters are required for normal nerve cell communication.
Lower levels of serotonin have been found in individuals suffering from depression and migraine headaches.
Vitamin B12 deficiency may cause peripheral neuropathy and lesions in the posterior and lateral columns of the spinal cord (subacute combined degeneration) and in the cerebrum. These lesions progress from demyelination to axonal degeneration and eventual neuronal death. These are serious complications, because they may not be reversed after replacement therapy with vitamin B12. The most frequent manifestations of peripheral neuropathy are paresthesias and numbness. The manifestations of a lesion in the spinal cord are a mixture of signs of a posterior column lesion (loss of vibration and position sense, and sensory ataxia with positive Romberg's sign) and those of a lateral column lesion (limb weakness, spasticity, and extensor plantar responses). Cerebral manifestations range from mild personality defects and memory loss to frank psychosis ("megaloblastic madness"). (NEJM)
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I hear and I forget. I see and I remember. I do and I understand.
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| santaclara
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GREAT EXPLANATION.APPRECIATING.
FROM WHERE DIDU GET MASH?
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| mash
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new england journal of medicine.......
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I hear and I forget. I see and I remember. I do and I understand.
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| santaclara
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when will u appear for exam?
is this boos is necessary for step1 or u just read it for knowledge.
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| mash
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im appearing in july n its not fr step1. I just read an article on B12 def n noted the salient features .
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I hear and I forget. I see and I remember. I do and I understand.
--Confucius
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| santaclara
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thanks for reply.
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| dr.shar
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hi bela,
please give the correct answer...
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| Malaysian
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whats formication??
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