mash
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A?
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| milu
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thank you mash
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| Sakaki-
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What's the mechanism by which this occurs?
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| mash
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aspirin irreversibly acetylates COX in d platelets thus inactivating it.
(platelets do not ve nuclei so they cant synthesize COX on their own)
TXA2 is not synthesized so platelet aggregation canot occur & BT is prolonged.
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| mjl1717
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ASA inhibits TXA2 (inhibits cyclooxygenase)
inhibits platlet function :arrow: increases BLEEDING TIME!
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