mjl1717
Forum Hero
Topics: 957
Posts: 5,461
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Some speculation but
1) intercalates DNA
2)inhibits topisomerase
3)forms free radicals which cause strand breaks in DNA
*cardiotox.
*dexrazoxane-free radical trapper -protects
*(ABVD)
*CellCycleNonSpecific along with alkylating agents
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| usmleasr
Forum Guru
Topics: 105
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=D> cool mjl...
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| dariush
Forum Elite
Topics: 20
Posts: 356
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also..
1) damages the lipid membranes
2) blocks DNA,RNA synthesis
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