mjl1717
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what is the formula for clearance?
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| mash
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clearance = ke * Vd = 0.7*Vd/t1/2
Vd is vol of distribution
t1/2 is half life
ke is 1st order elimination constt
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| krsna
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cl=blood flow thro the organ x extraction ratio.
extraction ratio = Ca - Cv / Ca
Ca- conc in aterial blood
Cv- conc. in venous blood
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