Quinn
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A 47-year-old male is seen in the medicine clinic with recently diagnosed mixed hyperlipidemia. An antihyperlipidemic is administered that favorably affects levels of VLDL, low-density lipoprotein (LDL), and high-density lipoprotein (HDL) and inhibits cholesterol synthesis. Which of the following agents did he receive?
A. Lovastatin
B. Colestipol
C. Niacin
D. Probucol
E. Neomycin
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| rida
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My initial thought Niacin as it effects everything but no flushed face in patient, so I think i'll go with A.
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| Quinn
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You were right at first with niacin....always go with your first thought....trust me.
Niacin blocks synthesis of VLDL and apo B in liver causing a decrease in VLDL, LDL, and TG in circulation. Sometimes you get an increase in HDL, or may remain at same level. I am not sure if flushing occurs in everyone or not. But you can administer aspirin to decrease it.
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| rida
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thanx, i always do make this mistake be second guessing myself and picking the wrong answer.
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