keepgoing
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A middle aged anatomy professor went to the hottest Indianapolis 500 race in decades and sat with the sun facing him; there was no breeze. He had a history of borderline high uric acid. When he became dehydrated at the race, it triggered the uric acid crystal formation in his foot. The foot became sore, red, hot and swollen; he could not walk on that foot or even fit into a regular pair of shoes. The race was great and he drank about 2 L of water and soda at the race and another couple of liters when he arrived home. Evidently that was not enough fluid because he was anuric for about 10–12 hours. His physician prescribes colchicine as an anti-inflammatory.A metaphase-blocking dose of colchicine functions through which of the
following mechanisms?
a. Depolymerization of actin
b. Depolymerization of myosin
c. Enhancement of tubulin polymerization
d. Inhibition of tubulin polymerization
e. Binding to and stabilizing microtubules
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| match2010
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