gag_pol_env
Forum Junior
Topics: 15
Posts: 42
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Can anybody tell how acetazolamide and progesterone are going to effect on central sleep apnea
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| dramer
Forum Senior
Topics: 14
Posts: 134
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i think it is contibute with acid- base disorders
acetazolamide___ decrease hco3c____
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| nightflight1945
banned
Topics: 32
Posts: 920
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progesterone increses the central drive for respiration --> increase RR .
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| Eagle_303
Forum Guru
Topics: 77
Posts: 655
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Acetazolamide ---------> metabolic acidosis ---------> stimulation of peripheral chemoreceptors ----> stimulation of respiratory center
Progestrone ----------- > direct Stimulation of respiratory center ----------- > increase in Tidal volume (not in the rate of respiration) --------- > Respiratory alkalosis in pregnancy
Note; MPA is used in Central sleep Apnea because of this action of progestrone
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