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Author9 Posts
  #1

why Ventricular septal defect and mitral regurgitation murmur don't change with squatting?(kaplan notes).

Thank you.

  #2

nobody knows?

I think kaplan may be wrong on this. I looked up other resources and all say squatting increases murmur intensity of VSD.

  #3

Thank u for informing us!

There are some subtle mistakes in Kaplan LN ,

In Kaplan Peds it is more than subtle !


  #4

I disagree that Kaplan is absolutely wrong. To understand we have to go for pathorphysiology.

Both of these murmurs are affected by :
  1. After load : if increases they increase ,if decrease they decrease
  2. Preload : if increase they increase ,if decreased they decrease

In fact squatting position there is
  • Compression of femoral vessels and abdominal aorta -----------> increase in after load
  • Compression of Femoral veins and IVC --------> First there is increase in venous return ------> leading to increase in preload ,then there is decrease in venous return due to persistant compression leading to Decrease in venous return :

In Squatting we can divide the effect on these murmurs in two phases :

First phase :
  1. Increase in after load
  2. Increase in preload

Result : murmurs are increased

Second phase
  1. Increase in after load -----> tending to increase in murmur
  2. Decrease in Preload -------> decreae in murmur

Result : nullification of both effects i.e No change

Best of luck


  #5

Eagle_303, you are very knowledgeable. thank you!

I agree with your explanation. However, when the question comes, which one do we choose? The increase in preload and afterload is an immediate effect and the second phase takes time to catch on. I guess the more reliable one is the first phase, isn't it?

By the way, how to distinguish MR and VSD?


  #6

MR and VSD are easy to recognize though both are holosystolic murmur .

MR = apical radiating to axilla

VSD = Left sternal border localized

Best of luck


  #7

The increase in preload and afterload is an immediate effect and the second phase takes time to catch on. I guess the more reliable one is the first phase, isn't it?

  #8

One should look at the changes in all the phases

But yes, people are usually interested in the sudden changes like sudden changes in positions (i.e. standing up anr squatting)

  #9

thank you, ngaybinhyen and Eagle_303.









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