dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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1) inc sex steroids, dec LH, dec FSH
2) dec sex steroids, dec LH, dec FSH
3) dec sex steroids, inc LH, inc FSH
4) inc sex steroids, inc LH, inc FSH
5) no change in sex steroids, no change in LH, dec FSH
Above choices can be used once or more than once
Match A-F with above choices
A) Primary hypogonadism
B) Pituitary hypogonadism
C) Postmenopausal female
D) Male on anabolic steroid
E) Inhibin infusion given to a male
F) GnRH infusion (constant rate)
G) GnRH infusion (pulsatile)
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| mjl1717
Forum Hero
Topics: 959
Posts: 5,467
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a)3
b)2
c)3
d)1
e)?
f)2
g)4
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| mash
Forum Fanatic
Topics: 147
Posts: 1,326
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a-- 3
b-- 2
c-- 3
d-- 1
e-- 5
f-- 2
g-- 4
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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u guys got it  totally correct answers from mash
D) Anabolic steroids-
dec LH- remove stimulus for Leydig cell -> Leydig cell atrophy -> no local production of testesterone (required for spermatogenesis) -> dec spermatogenesis. Testesterone normally doesnt provide feedback for FSh but if testesterone is very high, it will suppress FSH (not as much as LH)
E) Inhibin infusion
Inhibin- possible male contraceptive suppresses FSH (required for spermatogenesis) so spermatogenesis is inhibited.
F) GnRH if constant: intially increase plasma LH and FSH (receptors still present), with time: downregulation of receptors and LH and FSH levels decrease
G) Pulsatile GnRH prevents downregulation- chronic high levels of both LH and FSH
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