kpmle2
Forum Guru
Topics: 95
Posts: 512
|
A 60-year-old man presented with dysphagia,
facial flushing, and diarrhea. On examination
he was noted to have a goiter and mild cervical
lymphadenopathy. His physician orders thyroid
function tests and refers him to a surgeon. It is
now 8 months later and the patient is status
post total thyroidectomy, where the pathology
indicated medullary carcinoma. He is currently
being treated with thyroid hormone suppression
therapy. Which of the following is the
most significant risk factor for this form of thyroid
cancer?
(A) Alcohol
(B) Genetic risk factor
(C) Iodine exposure
(D) Radiation to the neck for enlarged tonsils
as a child
(E) Smoking
(F) Viral infection
|
| ngaybinhyen
Forum Guru
Topics: 23
Posts: 657
|
B
There is increasing evidence of genetic alterations in some thyroid cancers, especially in Chernobyl survivors
A family history of thyroid cancer is a risk factor for particular development of medullary thyroid cancer. This tumor occurs commonly within the spectrum of multiple endocrine neoplasia (MEN) syndromes 2A and 2B, and familial medullary thyroid cancer syndrome, all characterized by inherited mutations in the RET proto-oncogene
I hope I understand this correctly
Correct me if I'm wrong
|
| nightflight1945
banned
Topics: 32
Posts: 920
|
|
| young_doc
Forum Guru
Topics: 58
Posts: 737
|
B
This cancer is rare except for in the setting of MEN syndrome, in which case --> genetic.
___________________
First Aid is my Bible...
|
|
| |
| | | | |
