rida Forum Guru
Topics: 109 Posts: 721
| | 05/04/04 - 06:35 PM  
 
|   #1 |
What would you give to reduce reperfusion injury??
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| peekay Forum Guru
Topics: 102 Posts: 588
| | 05/05/04 - 06:08 AM  
 
|   #2 |
what is the answer rida
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| mdwannabe Forum Guru
Topics: 37 Posts: 1,133
| | 05/05/04 - 07:13 AM  
 
|   #3 |
may be Ca channel blocker?
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| rida Forum Guru
Topics: 109 Posts: 721
| | 05/05/04 - 11:32 AM  
 
|   #4 |
The answer is Antioxidants.
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| dxtxpx Forum Guru
Topics: 259 Posts: 1,233
| | 05/05/04 - 11:46 AM  
 
|   #5 |
Could u please explain this in terms of clinical scenario? thanks :|
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| rida Forum Guru
Topics: 109 Posts: 721
| | 05/05/04 - 12:08 PM  
 
|   #6 |
Dxtxpx, i actually don't have an example in a clinically oriented format, however, my guess would be that it would be related to myocardial infarction, since this injury is related to reperfusion of ischemic tissue. According ot robbins pathology, there is no defineite mechanism as to why reperfusion of ischemic tissues causes injury, but it produces free radicals, maybe because not ALL cells die during this ischemic episode but rather are biochemically compromised so if perfused can result in formation of free radicals with the newly oxygentaed blood causing MORE damage. Hence antioxidants can be given to a patient before reperfusing their ischemia to prevent formation of free radicals. I hope this helps, this was also a board question, but i dont know how the question was asked but was just told to know that antioxidants are given in reperfusion of ischemic tissues. Hope this helps.
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| dxtxpx Forum Guru
Topics: 259 Posts: 1,233
| | 05/05/04 - 12:24 PM  
 
|   #7 |
thankyou rida. yeah i was thinking in MI terms too. good explanation 
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| rida Forum Guru
Topics: 109 Posts: 721
| | 05/05/04 - 12:28 PM  
 
|   #8 |

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