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Author10 Posts
  #1

C. Cefuroxime


  #2

c


___________________
VB

  #3

C.

Medications Commonly Associated with Esophagitis or Esophageal Injury

Antibiotics

Tetracycline
Doxycycline
Clindamycin
Penicillin


Antiviral Agents

Zalcitibine
Zidovudine
Nelfanavir


Bisphosphonates

Alendronate
Etidronate
Pamidronate


Chemotherapeutic Agents

Dactinomycin
Bleomycin
Cytarabine
Daunorubicin
5-fluorouracil
Methotrexate
Vincristine


Nonsteroidal Anti-inflammatory Drugs

Aspirin
Naproxen
Ibuprofen


Other Medications

Quinidine
Potassium chloride
Ferrous sulfate
Ascorbic acid
Multivitamins
Theophylline



Tetracycline, doxycycline, and its derivatives are by far the most common causes of pill-induced esophagitis, with almost as many cases reported as all other cases combined



  #4

good one
folloup questions guys same topic
what would you do next in this case?

___________________
As a general rule, the better it felt when you said it, the more trouble it's going to get you into.

  #5

1. Next step: barium contrast swallow

2. Best Dx test: endoscopy

ATB-induced: Symptoms typically last several days to several weeks. Ulcerations may vary in appearance but are typically small and superficial located in the mid esophagus just above the aortic arch or left mainstem bronchus

3. Rx/prevention in chemotherapy: no treatment has been proven effective

- amifostine

- sucralfate

4. On the basis of the sometimes normally slow transit of medications through the esophagus, particularly for gelatin capsules and larger tablets,

(a) Medications should be swallowed with at least 8 ounces of a clear liquid;

(b) patients should remain upright for at least 30 minutes following ingestion

(c) in patients with potential underlying increased risk (e.g., inability to follow the previous instructions, poor esophageal motility, anatomic compromise of the esophageal lumen), search for alternative safer medications or carefully weigh the risks and benefits of this medication against the disease for which this medication is necessary


  #6

ngaybinhyen wrote:
1. Next step: barium contrast swallow

2. Best Dx test: endoscopy

ATB-induced: Symptoms typically last several days to several weeks. Ulcerations may vary in appearance but are typically small and superficial located in the mid esophagus just above the aortic arch or left mainstem bronchus

3. Rx/prevention in chemotherapy: no treatment has been proven effective

- amifostine

- sucralfate

4. On the basis of the sometimes normally slow transit of medications through the esophagus, particularly for gelatin capsules and larger tablets,

(a) Medications should be swallowed with at least 8 ounces of a clear liquid;

(b) patients should remain upright for at least 30 minutes following ingestion

(c) in patients with potential underlying increased risk (e.g., inability to follow the previous instructions, poor esophageal motility, anatomic compromise of the esophageal lumen), search for alternative safer medications or carefully weigh the risks and benefits of this medication against the disease for which this medication is necessary




C. Cefuroximeis the correct answer.

BTW ,

Next step in such a patient is to stop the drug and if the patient doesnot response to drug withdrawal , then I agree with ngaybinhyen

However doing esophagography or esophagoscopy in all patient woth symptoms of esophagitis and a definite insulting agent , is not correct .


  #7

I don't understand the last line in your text, nightflight.
Can you please explain more?

  #8

It means when there is a clear reason for patient's symptoms of esophagitis (drug here) , why should we do endoscopy or ... .

Please forget about corrosive agents that endoscopy should be done if first 12-24 hours /not for Dx but for assessment of the amount of damage.


  #9

Thanks
I think I'll get it when I do the Q

  #10

smiling facesmiling face








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