rubensssss
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Are progesteron and estrogen coming from Placenta and testes?
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Ruben sssss
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| mash
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i m sure estrogen is secreted frm both
not sure abt progesterone secretion frm testes
i think it is not.......
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| mani
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i dont think estrogen is produced in testes either. its production needs "aromatase" which is not there is testes. progesteron too is not produced in testes.
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| mash
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sertoli cells hv aromatase activity
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| rubensssss
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Thanks mash so you got the answer. Progesteron and estrogen has also their source in TESTES.
Thanks mash.
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Ruben sssss
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| mani
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i still doubt it. my refrence is here brs physio
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| rubensssss
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Well the boo that I am reading from is FA page 365.
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| mani
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see guys, brs page 296 "aromatization to produce estrogens occurs in ovaries and placenta, but not in adrenal cortex or testes!!"
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| mash
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1/3rd of estradiol in males is frm sertoli cells and remainder arises frm peripheral conversion in adipose ts.
Both sertoli cells n adipose ts ve aromatase activity.
increased estradiol in bld is a sign in sertoli cell tms in affected males.
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| mani
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mash plz check the refrence that i ve given and tell me ur reference. i m really confused.
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| mash
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mani, its in kaplan physio........
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| Sakaki-
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According to Greenberg's Basic and Clinical Endocrinology (Lange), estradiol is produced in the testes (<20), whereas the remaining 80% is derived from peripheral conversion.
(There's no mention of progesterone being produced from testes though).
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| mani
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progesteron has to be produced in testes bcaz its an intermediate in androgen synthesis. FA also says that estrogen is synthesized in testes but brs doesnt agree and till now i havent seen any such gross mistake in brs. thats why i m confused
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