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Author5 Posts
  #1

After a meal, blood glucose enters cells and is stored as glycogen, particularly in the liver. Which of the following is the donor of new glucose molecules in glycogen?


A. UDP-glucose-1-phosphate

B. UDP-glucose

C. UDP-glucose-6-phosphate

D. glucose-6-phosphate

E. glucose-1-phosphate

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  #2

its UDP glucose

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  #3

that is what I thought....the answer given was "c"
doesn't make sense to me...explaination below:

Blood glucose is rapidly converted to glucose-6-phosphate upon entering cells by hexokinase or, in the case of the liver, by glucokinase. Glucose-6-phosphate is in equilibrium with glucose-1-phosphate via the action of phosphoglucomutase. Glucose-1-phosphate is activated by UTP to form UDP-glucose, which is added to glycogen by an -1,4 linkage in the presence of glycogen synthase. To increase the solubility of glycogen and to increase the number of terminal residues, glycogen-branching enzyme transfers a block of about 7 residues from a chain at least 11 residues long to a branch point at least 4 residues from the last branch point. The branch is attached by an -1,6 linkage.

still seems like UDP-glucose is the right answer

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  #4

UDP- glucose

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  #5

I think we are right........most directly it is UDP-glucose. Besides G-6P converted to G 1-P, then linkage to UDP

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