mjl1717
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Its a general term meaning failure of fusion of vertebral arches(also called neural arches)
Important because it tells if one knows the terminology
It combines anatomy and path
Meningitis or Meningomyelitis can arise (probably group B Strep or E.Coli)
Briefly in the 3rd week--we get the neural plate--neural groove
neural fold and neural tube
the cranial part becomes the brain the caudal part becomes the spinal cord.
We then jump to the neuropores -failure of the anteriorpore to close results in anencephaly-(week 4-day 25), failure failure of the posterior neuropore to close results in spina bifida.( the 4th week-day 27)
mildest
Spina bifida occulta-defect in fusion of vertebral arches-you may see
a dimple or hair. (The cord and meninges are normal)
10% of the population
Group Spina bifida cystica
Spina bifida with meningocele-the meningeal sac( also called
arachnoid ) filled with CSF project thru vertebral defect
(Cord in normal position)
Spina bifida with meningomyelocele-occurs when the narrow
neck sac with includes the meninges and the spinal cord
or cauda eqina herniate thru vertebral defect to form a
large sac. Here you can have nerve paralysis to rectum,
bladder and lower limb causing "frog leg appearance"
due to flexion of iliopsoas.(femoral/sciatic n.paralysis)
Group Spina bifida aperta
Spina bifida with myelocele also calle spina bifida with
myeloschisis or simply myelocele--results in an open tube
which lies open on the surface of the back. The neural folds
remained open& CSF leaks on the surrounding skin. Poor
prognosis. Bladder,rectum and lower limbs are paralyzed
causing the "frog leg appearance" Arnold Chiari syndrome
is usually present.
Rachischisis is only a small fold of neural tissue
Anencephaly as mention is failure of the anterior neuropore to close
and occurs in 1 in 1000 births
Pictures are worth a thousand words and BRS Neuro or Embryo may be helpful.
The action of Spina bifida is usually around L5 to S1
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| peekay
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THANKS mjl1717.
these topics are very exam relevent. i heard they give u a embryo diagrame and than ask for the origin of the defect.
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| mjl1717
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Yes your acknowledged peekay it is considered Hi Yield.
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| Bela
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very nice summary mjl! excellent job. thnx!
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| Bela
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I was absorbing mjl's info but also read the info that this other guy had posted on a different topic. He was saying that Spina Bifida Aperta is the same thing as Meningomyelocele whereas mjl is saying that it's the group of spina bifida w/myelocele. Can someone clarify? :? Thnx
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| mjl1717
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Thx -Good catch Bela- your probably talking and my buddy kalsam
[In so many words "we are in the same boat"] I used a Pretest
Pathology as my reference and I noticed they used 2 references-Cotran,p 1300 and Robbin 1449-1450
I think aperta means to remain apart or open. (very early in development)
I didnt copy this correctly
The most severe form of spina bifida, spina bifida aperta or myeloschisis, results from complete failure of fusion of the caudal end of the "Neural Plate", which lies open on the skin surface. So the word neural plate should replace neural folds.. I hope this sheds some light on the subject.
Im talking as early as the neural plate in development /I believe most books would say meningomyelocele is herniation of cord and meningeal sac thru the vertebral defect which is later in development with neurologic defects. "Detailed Stuff"
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