drhouse
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Methyl dopa can be used in parkinson dis,,,, then i dont understand why it can cause parkinson. anybody pl explain... similarly why reserpine causes parkinson??
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| nightflight1945
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reserpine empties the synaptic endings from NTs so there is not any DOPAMINE LEFT
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| liliaeliz
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reserpine irreversibly bind to storage vesicles of neurotransmitters such as dopamine, norepinephrine, and serotoni, reserpine has a peripheral action in many parts of the body, resulting in a preponderance of the cholinergic part of the nervous system
Reserpine almost irreversibly blocks the uptake (and storage) of norepinephrine ( noradrenaline) and dopamine into synaptic vesicles by inhibiting the Vesicular Monoamine Transporters
methyl dopa stimulate alpha 2 receptor , inhibiting release of neurotransmitters
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| drhouse
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ohh okay,,, it seems to be pretty simple but i was really confused... thanks to both of u
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