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Kaplan Qbank USMLE



Author3 Posts
  #1

what does it binds to? what is its role ?

  #2

It seems to control gene expression

1) it has an alpha helix
2)it contains one zinc atom bound to 4 cysteine amino acids
3)it has hormone binding region
4)the 70 amino acid long region binds to specificlly to DNA segments
5)examples are -a)Transcription factor engages RNA polymerase II to the
gene
b)SpI
c)glucocorticoid receptor,estrogen receptor, thyroid
receptor, retinoic acid receptor, Vit D3 receptor.

Hope this helps

___________________
Smell the coffee! "Is That an Osler move??"

  #3

u r right mjl.

Now let us put it into very specific Q about the central Zn atom in an alpha helix...what binds to it ?

a. DNA
b,RNA
c. steroid hormone
d.proteins

:arrow: answer c







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