asmi
Forum Hero
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What is the role of CD 28 and CD 40 ?
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| rida
Forum Guru
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CD 40 is involved in isotype switching, and binds CD40 on B cells and is a marker on T cell. CD 28 is also a marker on T cell, and is a costimulatory molecule that is required for activation of T cells. It binds b7 on B cells.
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| mdwannabe
Forum Guru
Topics: 37
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CD 28 on T cell...interacts with CD 80/86 on B-cell. results in T cell actication and differentiation.
CD 40 on B-cell, interacts with CD40 ligand (also known as CD 154) on T cell , isotyoe switch enabling.
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| Alina T
Forum Elite
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i hate hate hate CD questions......... :cry:
:lol: :wink:
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| asmi
Forum Hero
Topics: 1043
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cool mdwannabe 
keep it up :idea:
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