kpmle2
Forum Guru
Topics: 95
Posts: 512
|
A 42-year-old woman who smokes tobacco is
found to have acute-onset respiratory distress
and tachycardia 4 hours after a nonemergent
cholecystectomy. She is subsequently treated
for a symptomatic pulmonary embolism. She is
begun on low-molecular-weight heparin and
warfarin while in the hospital and is supplied
with subcutaneous doses of low-molecularweight
heparin to take at home for a total
course of 5 days, in addition to the warfarin that
she will take for at least 6 months. The initial 5
days of overlap of both heparin and warfarin is
necessary because at the beginning of treatment,
warfarin actually leads to hypercoagulability.
What is the underlying reason for this?
(A) There is an initial increase in vitamin
K–dependent coagulation factors
(B) Venous valvular insufficiency is exacerbated
during the first 3 days of warfarin
therapy
(C)Warfarin causes a more rapid drop in the
levels of proteins C and S than factors II,
VII, IX, and X
(D)Warfarin induces resistance of factor V to
degradation by activated protein C
(E) Warfarin leads to an initial increase in
platelet aggregation
|
| nightflight1945
banned
Topics: 32
Posts: 920
|
Warfarin causes a more rapid drop in the
levels of proteins C and S than factors II,
VII, IX, and X
esp in those who has inherited deficiency of protein C/S , it can cause a bunch of problems.
|
| angel23
Forum Guru
Topics: 42
Posts: 980
|
C
___________________
God please help me....Haribol!
|
| Eagle_303
Forum Guru
Topics: 77
Posts: 655
|
Is it really possible to develop PE just after four hrs of surgery ??
Help is requested
|
| nightflight1945
banned
Topics: 32
Posts: 920
|
although the classic timeline is DVT 3-5 days and PE 5-7 days , however many if not most cases of DVT occur intra-operative esp when it lasts more than 4 hours and I think it is completely possible!
|
|
| |
| | | | | |
