hopeofglory87
Forum Senior
Topics: 23
Posts: 71
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36. A previously healthy 52-year-old man comes to the physician because of a 3-month history of increased urinary volume and increased urinary frequency at night. He has had a 6.8-kg (15-lb) weight loss during this period despite no change in appetite. His father has hypertension, and his mother has hypertension and type 2 diabetes mellitus. He currently weighs 95 kg (210 lb) and is 178 cm (70 in) tall. His blood pressure is 160/85 mm Hg in both arms. Examination shows no other abnormalities. His nonfasting serum glucose level is 280 mg/dL. Which of the following serum levels is most likely to be increased in this patient?
A
) Bicarbonate
B
) Glucagon
C
) HDL-cholesterol
D
) Insulin
E
) Ketones
Is this B or D?
I chose B,,,I think I saw something like this in step 1 UW
But It could also be NIDDM which makes D a possible answer
Could someone clarify when glucagon will be the answer and when insulin will???
May be type 1 : Decreased Insulin, Increased Glucagon
type 2 : Increased Insulin...But what happens to glucagon level in type 2?
AAAAAHhhhhhhhhhhhhhhhhhhhhh
I'm getting really confused!!
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| Eagle_303
Forum Guru
Topics: 77
Posts: 655
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Type II DM is characterised by hypeinsulinemia. Because it is primarily receptor or post-receptor defect.
This is hyperinsulinemia in type II DM that
- There is no ketosis
- There is no weight loss
- There is atherosclerosis /HTN
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| hopeofglory87
Forum Senior
Topics: 23
Posts: 71
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What about glucagon in type 2 DM?
I guess it will probably decrease in response to hyper glycemia
BUT then in type 1, why high glucagon???
(It says in UW that for DKA to occur it's the deficiency in insulin and increase in glucagon that are responsible for DKA)
Could somebody help me understand?
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| Eagle_303
Forum Guru
Topics: 77
Posts: 655
|
Glucagon ,Growth Hormone and ACTH are stress hormones and these are released whenever there is stress on the body .
DKA has always some stress like infection or dehydration leading to shock or trauma physical or psychological
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