keepgoing
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This 44 year old woman developed insulin dependent Diabetes Mellitus at age 14. At age 32, she was found to be hypothyroid due to Hashimoto's thyroiditis. At about the same age, she had blurred vision, tingling feet, and a propensity to sprain the left ankle. At age 39, there was tingling, weakness and clumsiness of the left limbs. An MRI showed changes consistent with multiple sclerosis. The most logical biological treatment approach in this patient would be to:
a. stimulated CD4 and CD 8-Tcell activity
b. suppress CD4 and CD 8-Tcell activity
c. stimulate CD4 and suppress CD 8-Tcell activity
d. suppress CD4 and stimulate CD 8-Tcell activity
e. attempt to maintain the current activity of CD4 and CD 8-Tcells
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I am not sure what to do with B-cells...
I will go with D.
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| GoodGirl
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AAAhhh, immunology
will go with B.
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| keepgoing
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D is correct answer.
CD4 T-cells release interleukin-2, interferon-gamma,and lymphotoxin all of which contribute to the cascade that produces the pathology of MS, so you want to suppress them.
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Keepgoing! So, in this question we should think only about MS? I thought we need to condiser DM and Hashimoto also... As I know MS and DM involve T-cell...but not sure about Hashimoto... In Kaplan, both cellular and humoral immunity involved...
So, if you can put some light for me here...Thanks
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Forum Guru
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Oh... and why we need stimulate B-cells?
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