mjl1717
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Can anyone briefly explain Bacterial transformation?
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| rida
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Transformation is basically uptake of naked DNA from the environment by competent cells. Competent cells are those that are able to bind short pieces of DNA to the envelope and import them into the cell. These cells become competent under certian environmental conditions. A dead cell can release its DNA to a competent cell which will bind it. This DNA has to be stabalized in the new cell because if its not, it can become the target of exonucleases, therefore, it must go through the process of homologous recombination which stabalizes the genes. A new cell has now been made.
Production of capsulated strep pneum from a non encapsulated strep is an example of transformation. Hope this helps 
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| mjl1717
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Thx
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| peekay
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GOOD EXPLANATION . I UNDERSTAND IT BETTER NOW.THANKS RIDA
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| rida
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| kalsam
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Some medically important spieces which undergores natural transformation...
Haemophilus
Streptococcus
Nesseria Gonorrhea
H.Pylori..
Just to add some more..
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| Malaysian
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By undergoing transformation what exactly is changing in the bacteria......is it all gaining capsules?And what about H.pylori which doesnt have a capsule?
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