Bela
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30 yo male develops extensive pruritic wheals following ingestion of seafood to which she’s allergic. Bx would probably show:
a) Dilated Superficial Lymphatic Channels
b) Granular complement and IgG @dermal/epidermal junction
c) Microscopic blisters
d) Munro microabscesses
e) Solar elastosis
Do u know what diseases u see the rest of the answers in?
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| rida
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b.....
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| Bela
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No rida! IgG @ dermal/epidermal junction is for SLE. Try again! 
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| sing
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C
it is the type 1 hypersensitive reaction. there is histamine etc staff release. so should be microscopic blisters. am i right?
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| mash
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I think its urticaria
so ans should be microscopic blisters
wats d ans?
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| usmleasr
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a is the ans..dilated lymphatic channels
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| mash
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can u explain?
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| Bela
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a) Dilated Superficial Lymphatic Channels
b) Granular complement and IgG @dermal/epidermal junction (SLE)
c) Microscopic blisters (dermatitis herpatiformis)
d) Munro microabscesses (psoriasis)
e) Solar elastosis (actinic keratosis)
Ans: A Urticaria (hives) are pruritc wheals that form after mast cells degranulate and trigger localized dermal edema w/dilated superficial lymphatic channels. (not my explanation
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| mash
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Urticaria occurs following release of histamine, bradykinin, kallikrein, or acetylcholine, resulting in intradermal edema from capillary and venous vasodilation and occasional leukocyte infiltration.
http://www.emedicine.com/emerg/topic628.htm
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| dr.shar
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a) Dilated Superficial Lymphatic Channels
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