shazbaz
Forum Junior
Topics: 15
Posts: 51
|
a 63 year old woman has chest pain while climbing stairs of her office building. She sits down and takes some medication, after which she is able to continue. Which of the following is the mechanism of action of this drug?
a. decreased afterload
b. decreased preload
c. increased afterload and preload
d. increased preload
e. increased contractility
|
| shazbaz
Forum Junior
Topics: 15
Posts: 51
|
also please explain why
|
| DR_K
Forum Senior
Topics: 32
Posts: 150
|
B) decrease preload which is the mech of action of nitroglycene.
coz A)dec after load is the mech of most anti hypertensive drugs not anginal.
C)not a beneficail effect on angina
D)same as c
E) this is the mechanism of positive ionotropic drug which inc contractility and if u inc the contractility of heart if will further inc the oxygen demand of heart which will worsen the situation.
so ans is B.
___________________
good luck(Y)
|
| DR_K
Forum Senior
Topics: 32
Posts: 150
|
for this question u should know which drud she took which in the case is sub-ligual nitrate(nitroglycerin).
___________________
good luck(Y)
|
| DR_K
Forum Senior
Topics: 32
Posts: 150
|
and forgot to mention that in low doses nitro cuses only "venodilation"(dec preload)but in high doses can also coz atreriolar dilation which we dont consider in therapeutic doses.
___________________
good luck(Y)
|
| DR_K
Forum Senior
Topics: 32
Posts: 150
|
i think u should post this q on pharma forum rather than phsio
___________________
good luck(Y)
|
| DRFP
Forum Guru
Topics: 39
Posts: 709
|
This belongs in both its a combination q
You are to know the mechanism and the drug that affects the mechanism
its the way the boards are written
___________________
Knowledge should be shared not withheld.
|
|
| |
| | | | | | | |
