clar697
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In a 24-year-old woman, which of the following is the most likely to induce a shift in the normal balance of bone accretion and resorption toward net bone loss?
A) Bodybuilding and use of anabolic steroids
B) Eating a high-calcium diet
C) Living on a space station for the past 6 months
D) Metabolic alkalosis and chronic vomiting
E) Running 1-2 miles, 3 times weekly
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| match2010
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C?
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| hitesh
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C) Living on a space station for the past 6 months
'Cos of lack of sunlight
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| match2010
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NO ....not cuz of lack of sun ....cuz of decreased gravity which doesnt impose any stress on the bones thts why ..same reason why swimming will do such thing .....
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| hitesh
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how abt A) Bodybuilding >>> low estrogen levels? 
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| supra
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C
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| match2010
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well cant be A either as if you take anabloic steroids you will testosterone as well and tht checks IL-1 as well .moreover anabolic steroids are known to cause hepatic adenoma ......
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| match2010
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 why i said lack of sun for last 6 months wasnt a big issue cuz firstly there are so many countries where sun doesnt comes out for 7-8 months so acc. to this theory everyone shuld have the bone resorption ........yeah sun can play imp. factor but i think when its like 1-2 yrs or something ...
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| seharmd
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C
There is a relationship between bone mass and steroids (A) but C is definitely a better and definite answer.
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| littledoc
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what does metabolis alkalosis do to free Ca++ level ? & why?
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| LG
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so far i agree with hitesh ...A
bodybuilding and anabolic steroids are about building lots and lots of muscle and no fat....there goes your estrogen and your osteoclasts are on the loose
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| alirizvi
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whats the answer to this one ? It can be A or C
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| DrNickSaysHello
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C. Had to do some research. From wikipedia.
"Spaceflight osteopenia refers to the characteristic bone loss that occurs during spaceflight. Astronauts lose an average of more than 1% bone mass per month spent in space." "These effects can be minimized through a regimen of exercise."
"Female-specific side effects [of anabolic steroid abuse] include increases in body hair, deepening of the voice, enlarged clitoris, and temporary decreases in menstrual cycles." "Weight lifting reduces the risks of osteoporosis."
I don't like this question, because I've seen similar questions that ask about female patients with anorexia and excessive exercise having premature bone loss.
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