mash
Forum Fanatic
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a man is affected with tyrosinase-negative oculocutaneous albinism (autosomal recessive). Based on this information alone, what is the probability that his grandson and his great-granddaughter are both heterozygous carriers of the albinism gene?
can anyone ans this with an explanation?
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| Malaysian
Forum Guru
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Posts: 778
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I don't think its possible to calculate as there isn't ample information.
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| nyimg
Forum Newbie
Topics: 9
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Since he has it (aa), his child that delivered his grandson must be a carrier (at least). So his grandson should have 1/2 probability and his greatgranddaugther should have 1/4 probablity as a carrier.
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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well according to this site, the answer is 1/8 and they didnt give any explanation:
http://medgen.genetics.utah.edu/tests/test11995/q...
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| Ahab
Forum Elite
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Because they are asking the probality of both happening
1/2 *1/4 =1/8
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| Mars-Aris
Forum Elite
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here is my explanation :
1.all of his children will be carriers
2.50% of his grandchildren willl be heterozygus NO matter the female mate genotype (= if she is carrier, homozygus for recessive or dominant genes)
3.the same situation also for next generation
calculating --> 1/8
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