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Author9 Posts
  #1

An 82 yo woman, otherwise healthy for her age, has difficulty sleeping. Triazolam is prescribed for her at one-half of the conventional dose. Which of the following statements about the use of triazolam in this elderly patient is accurate?
A. Ambulatory dysfunction does not occur in elderly patients taking one-half of the conventional adult dose
B. Hypertension is a common adverse effect of benzodiazepines in patients over 70 years of age
C. Over-the-counter cold medications may antagonize the hypnotic effects of the drug
D. She may experience amnesia, especially if she also drinks alcoholic beverages
E. Triazolam is distinctive in that it does not cause rebound insomnia on abrupt discontinuance

The most likely explanation for the increased sensitivity of elderly patients to a single dose of triazolam and other sedative-hypnotic drugs is
A. Changes in brain function that accompany aging process
B. Decreased renal function
C. Increased cerebral blood flow
D. Decreased hepatic metabolism of lipid-soluble drugs
E. Changes in plasma protein binding


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  #2

from Trevor/Katzung review

sorry, i dont know the answer, the pdf book i have is missing in the answer pages,

if you can discuss your answer, that'd be great


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  #3

no takers for this stupid question sad


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  #4

i think changes in the brain (A)function due to aging because also levadopa cause severe psychosis in elderly esp after 70 bcoz of degenerative changes.so thats how i m relating this question to it:S.


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  #5

I think its A

  #6

As per Katzung and Trevor..... The answers are D and A resp.....

  #7

its D side effect includes amnesia definitelynod

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  #8

D. She may experience amnesia, especially if she also drinks alcoholic beverages

anterograde amnesisa ,, date rape


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VB

  #9

B. Decreased renal function


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VB







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