clar697
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An 11-year-old boy has been passing large volumes or urine and has been extremely thirsty over the past 10 days. He has lost a considerable amount of weight despite having a good appetite. During the past 2 days, he has become increasingly drowsy, lethargic, and difficult to arouse. Respirations are deep and rapid. His blood pressure is 100/60 mm Hg while supine and 40 mm Hg/undetectable while sitting. In addition to glucose, which of the following is the principal fuel oxidized in his brain?
A) Alanine
B) Glutamate
C) Glycogen
D) Beta-hydroxybutyric acid
E) Palmitate
F) Triacylglycerol
I chose D, b-hydroxybutyric acid (ketones). Is this correct?
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| atulkalanuria
Forum Newbie
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yeh diabetic ketoacidosis 
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| Karime
Forum Guru
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 "In the fasting state the liver converts excess acetyl coA from B-oxydation of fatty acids into ketone bodies, acetoacetate and 3-hydroxybutyrate (beta-hydroxybutyrate) which are used by extrahepatic tissues" ............from Kaplan
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| usmlekiller
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D 
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| zwmack
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The brain uses glucose primarily and keytones second. So D seems correct.
Quick question as an aside. Can acetate be considered as a keytone?
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| SpeaksSoftly
Forum Senior
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Nope, acetate is an ester, however acetone is a ketone. It's all about the functional group on the main carbon.
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| zwmack
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Thanks. I may have gotten a question wrong on my exam. Oh wells!
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