DrVirgo Forum Hero

Topics: 1096 Posts: 3,515
| | 07/07/08 - 11:45 AM  
 
   
 
|   #1 |
10. A screening test is applied to a population of 1000 in which the prevalence of disease Y is 10%. The sensitivity of this test is 96%, and the specificity is 92%. The diagnostic workup for each person found to have a true positive result in the screening test costs $50. A newer screening test has the same sensitivity (96%) but an improved specificity of 96%. However, the new test costs 50 cents more per test than the older screening test. If the newer screening test were to be used, how much money would be saved or lost? (A) $1300 saved (B) $1300 lost (C) $500 saved (D) $1800 saved (E) $500 lost
___________________ Our greatest glory is not in never falling, but in rising every time we fall.
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| DrVirgo Forum Hero

Topics: 1096 Posts: 3,515
| | 07/09/08 - 08:06 AM  
 
   
 
|   #2 |
Please attempt this one... Let me know how you calculated the right answer. I will post the correct answer with the entire explanation soon.
___________________ Our greatest glory is not in never falling, but in rising every time we fall.
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| hero Forum Guru
Topics: 42 Posts: 552
| | 07/09/08 - 10:01 AM  
 
   
 
|   #3 |
let see, new one is 0.5$ more expensive, and we want to screen 1000 ppl, what makes 0,5 x 1000 =500$ lost (i didn't try this as. test yet, saving it as a last assessment )
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| DrVirgo Forum Hero

Topics: 1096 Posts: 3,515
| | 07/11/08 - 08:50 PM  
 
   
 
|   #4 |
Its a bit more complicated than that... I got half way up to the 1800 part only, but then got lost... Here is the explanation: The correct answer is A. Regardless of which test is used, the entire population, or 1000 people, will be screened.We do not know the cost of the original test, but we know that the new test costs 50 cents more per application. Therefore, screening the population of 1000 will cost ($0.50 × 1000), or $500, more with the new test than the old. However, the specificity of the new test (96%) is higher than the specificity of the old test (92%).We know that the prevalence of disease Y is 10%, so 90% of the population, or 900 people, are disease-free. The original test will correctly identify 92%, or 828, of these 900 subjects, and there will be 72 false-positive results. Each person whose test result is falsely positive will need the diagnostic workup that costs $50 per person. The newer test will correctly identify 96%, or 864, of the 900 subjects who are disease-free, and there will be 36 falsepositive results. There are 36 fewer false-positive tests with the new test than with the old. Old Test New Test Positive test 72 36 Negative test 828 864 Actual nondiseased 900 900 The number of true-positive results remains unchanged because the sensitivity of the new test is the same as that of the old test (i.e., 96%). All of the subjects that test positive will require the $50 workup, and there will be 36 fewer of these with the new test. The savings resulting from not having to do the workups for 36 people is 36 × $50, or $1800.When the $500 in additional costs associated with the new test is subtracted from the $1800 savings, there is a net savings of $1300 if the new test is used.
___________________ Our greatest glory is not in never falling, but in rising every time we fall.
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