USMLEGladiator
2009 & still in race
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Posts: 509
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form1--------
20. A 72-year-old man comes to the physician because of a 7-month history of leg weakness and dry eyes and mouth. He also has had a 10.4-kg (23-lb) weight loss over the past 4 months despite no change in appetite. He has smoked one and a half packs of cigarettes daily for 50 years. He drinks 4 oz of alcohol daily. He has peptic ulcer disease and emphysema. Medications include cimetidine, theophylline, and low-dose prednisone. Examination shows mild ptosis. He has a barrel-shaped chest. Breath sounds are distant. There is moderate weakness of the proximal muscles of the lower extremities. Reflexes are absent. He has difficulty rising from a chair. Sensory examination shows no abnormalities. An x-ray film shows a hyperinflated chest and a 3 x 4-cm mass in the right hilum. His neurologic findings are most likely due to a lesion involving which of the following?
A) Muscle membrane
B) Parasympathetic nervous system
C) Peripheral nerve
D) Presynaptic neuromuscular junction
E) Sympathetic n
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| hero
Forum Guru
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a, Lambert-Eaton
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| dr19
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D-Eaton-Lambert
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| hero
Forum Guru
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Posts: 557
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you are right,
ACh release from the motor nerve terminal is impaired. The effect of ACh on the postsynaptic muscle membrane is normal.
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| Eagle_303
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Thread Extension :
1:There are three groups of drugs which can affect the same Ca-channels against which antibodies are formed .Which are these drugs ?
2:Which condition can lead to enhanced release of Acetyl choline ?
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| USMLEGladiator
2009 & still in race
Topics: 135
Posts: 509
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ya LEMS....DDDDDDDDD.
thx for replies
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Chance favors only the prepared mind. - Louis Pasteur.
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| mikky
Forum Elite
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dunno about the drugs but black widow spider venom increases Ach release...
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